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Blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II |
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Does not inhibit ACE, hence does not affect the response to bradykinin |
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Does not bind to or block other hormone receptors; important in cardiovascular regulation |
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HCT- Thiazide class Diuretic reduce sodium reabsorption |
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HCT-increases urination to return osmolarity to normal |
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May be administered with or without food |
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Initial only 1 tablet once daily |
